Losing Fat, Is It In Your Genes?

Leptin Paradox:


The leptin paradox: refers to the phenomenon where increased levels of the hormone leptin, which is supposed to regulate energy balance and inhibit hunger, do not lead to the expected weight loss in obese individuals.

Instead, these individuals often experience leptin resistance, where the body doesn't respond effectively to the hormone.

This leads to continued overeating and difficulty in losing weight.


Key Points of the Leptin Paradox:

  1. Leptin's Role:

    • Leptin is produced by fat cells and communicates with the brain to regulate appetite and energy expenditure.
    • When fat stores increase, leptin levels rise, signaling the brain to reduce appetite and increase energy expenditure.
  2. Leptin Resistance:

    • In obesity, despite high levels of leptin, the brain does not receive the correct signals to reduce appetite and increase energy expenditure.
    • This condition is known as leptin resistance.
  3. Consequences:

    • Leptin resistance leads to a continued feeling of hunger and reduced energy expenditure, making weight loss difficult.
    • The body's inability to respond to leptin properly contributes to the maintenance of obesity.
  4. Factors Contributing to Leptin Resistance:

    • Inflammation: Chronic inflammation in obese individuals can impair leptin signaling.  This stems from high carb intake and high body fat accumulation.
    • High-Carb Diet: High Insulin and body fat will disrupt leptin signaling pathways.
Grass-Fed Pur Zealander contains all 9-EAAs.
The Fix
1. Eat Protein
Higher protein diets increase leptin production by influencing leptin gene expression.
These diets also improve leptin sensitivity and insulin sensitivity, making you feel fuller longer after meals.
Over time, a high-protein diet helps with fat loss and maintenance by making the body's leptin more effective at regulating appetite and energy use.

Grass-Fed Pur Zealander contains all 9-EAAs.

  • Highest quality Bioavailable grass-fed protein
  • Highest quality natural ingredients
  • Sourced from New Zealand cows that graze on all-natural, pesticide-free farmlands within a country that upholds the strictest quality controls
  • Free from growth hormone and antibiotics
  • Whey protein derived from grass-fed cows has a higher protein concentration, has up to 5x higher CLA, and has more Vitamin A & E, beta-Carotene, and Omega-3, when compared to grain-fed cows.
Omega-3 Pharmaceutical Fish Oil
2. High DHA Fish Oil
Boosting your Omega-3 intake, especially DHA, helps improve leptin levels and sensitivity by reducing inflammation in the brain.
Omega-3s lower triglyceride levels, which enhances leptin transport and signaling.
DHA also influences genes involved in leptin production, helping regulate appetite and energy balance more effectively.
Most omega-3 fish oil supplements contain primary EPA, not DHA. So if you supplement, use Omega-3 Cold Processed Pharmaceutical Fish Oil  It contains 1200 mg of leptin-balancing DHA - Pharmaceutical grade